Cellular or Area Based Quantification Analysis Services
CD BioSciences provides high-quality quantitative cellular and area based image analysis services to our clients. We utilize advanced image processing and analysis techniques to perform detailed quantitative analysis of cellular and tissue regions in images to obtain objective and accurate standardized results and statistical analysis data. Our services are widely used in biomedical research, drug discovery, cancer research, tissue engineering, and other fields to help our clients gain a deeper understanding of cell and tissue characteristics and advance research.
Cellular or Area Based Quantification Analysis Services
CD BioSciences provides clients with cellular and area based imaging quantification analysis services using microscopic observation and digital imaging techniques to obtain high quality image samples. We employ computerized image processing algorithms for image preprocessing and enhancement to ensure that the images analyzed are of excellent quality. Our services help our clients obtain accurate, quantitative image results for the cellular and tissue areas of clients' interest.
Quantitative image analysis services
We will utilize staining analysis techniques and machine learning to provide quantitative image analysis services to our clients, which mainly include:
➢ Analyze the staining intensity and tissue size or shape differences within a sample set to provide clients with accurate quantitative data.
➢ Learn what the client is studying and provide standardized results and statistics to help the client obtain quantitative features of interest.
➢ We can identify and quantitatively measure differences between different tissue regions, providing insight into tissue changes due to tumor growth, mesenchymal infiltration, or necrotic foci formation.
Cellular or area based IHC/IF quantification analysis services
CD BioSciences will provide clients with cellular or area based IHC/IF quantification analysis services, including serial tissue sections and immunostaining. By staining for different biomarkers, researchers can observe and analyze the expression of specific markers in cells and tissues. Our services mainly include:
Biomarker evaluation services
➢ Area distribution assessment
Align multiple tissue sections using an image alignment method to assess the regional distribution of multiple biomarkers in the tissue to obtain more comprehensive information for the client.
➢ Calculate the percentage of positive biomarkers
We can quantify positive biomarkers in tissue sections and calculate its percentage in cellular or area.
Other quantification analysis services
| Services | Details |
| Quantification analysis of tumor invading lymphocytes | Through application of immunohistochemical staining (IHC) and multiplex immunofluorescence (mxIF) techniques, we can analyze lymphocyte invasion in tumor tissues and perform distance analysis. |
| Fatty acid accumulation in liver / NASH studies | Tissue sections and immunohistochemical staining (IHC) techniques help researchers to quantitatively analyze fatty acid accumulation and NASH in the liver, including: ➢ Quantification analysis of fatty acid accumulation. ➢ NASH pathology characterization ➢ Molecular marker expression analysis ➢ Cytokine and inflammatory marker analysis |
| Myofiber/adipocyte size and distribution analysis | Analysis of myofibers and adipocytes in tissue sections to understand the size and distribution to study diseases or physiological processes associated with muscle and adipose tissue. |
| Spleen highly multicellular phenotyping | Perform highly multiplexed cellular phenotyping of spleen tissue to observe the expression of multiple cellular markers and investigate spleen function and processes related to the immune system. |
| Concentric partitioning/distance-based analysis of blood vessels and tumor margins | Perform concentric zoning or distance-based analysis of blood vessels and tumor margins to understand the distribution of blood vessels and tumor margin characteristics, providing important information for tumor research. |
Customized quantification analysis services
According to clients' needs and research objectives, we will provide customized analysis solutions. Provide clients with customized quantification analysis services for highly multiplexed imaging datasets, which includes:
➢ Imaging mass spectrometry flow cytometry data
➢ Multiplexed ion beam imaging data
➢ Multiplexed immunofluorescence data
Manual identification of cell types
In order to provide more detailed quantitative data and analysis results, our professional team will also review the images carefully to manually label and identify specific cell types for our clients.
CD BioSciences has a professional team and advanced imaging equipment. The whole process of cellular or area based quantification analysis services is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us.
*If your organization requires the signing of a confidentiality agreement, please contact us by email.
Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!