Services Overview

CD BioSciences offers a wide range of functional imaging services of nervousl tissues to meet the needs of neuroscience research. Our high-speed microscopy imaging technology enables the study of rapid and dynamic processes such as cellular transport and synapses. At the same time, our technology can provide researchers with high contrast and resolution images by reducing fluorescence scattering and background signals. These services help clients study neural activity, connectivity, and the effects of drug interventions. In addition, with our advanced technology, researchers are able to explore the functions of the brain's nervous tissue and the spinal cord's nervous tissue more comprehensively.

Fig. 1 Neurons communicate with each other using electrochemical signals.

Imaging of Nervous Tissue Functions

Brain nervous tissue functional imaging services

Understanding the brain is a challenging scientific task, with difficulties stemming largely from the extraordinary complexity of brain structure and the limitations of existing technological tools. CD BioSciences provides nervous tissue functional imaging analysis services, which help researchers to explore in-depth the functioning of the brain's neural tissues by observing in vivo samples non-invasively and with micro- and nanometer-scale resolution. Our services include:

High resolution whole brain neural network structure imaging and reconstruction

Using optical microimaging combined with techniques such as fluorescent labeling and tissue transparency, CD BioSciences enables high-speed and deep structural imaging and reconstruction of whole brain neural networks. We provide our clients with transparent whole-brain microscopic imaging data from animals and utilize intelligent methods for neural network reconstruction.

In vivooptical imaging of brain functions

With two-photon imaging, three-photon imaging, and optical technologies, CD BioSciences has further enhanced the depth of penetration for optical imaging in the brains of living, awake animals. Utilizing these technologies, we are able to help researchers obtain information on the electrical activity of the following structures without disrupting neural connections, including:

• Deep brain regions of neurons
• Subcellular organelles (e.g., cell body, dendrites, axon)

3D optical neurofunctional imaging services

CD BioSciences utilizes 3D Optical Neurofunctional Imaging to help clients obtain more comprehensive information about neural network activity. Our technology is capable of recording large-scale neuronal functional activity at high speeds in the brains of awake animals, while maintaining high resolution of individual neurons. Our service is suitable for animal models such as mice, and is able to record calcium activity signals from massive neurons simultaneously over large areas, helping researchers to study the dynamic function of brain neural networks, which can be mainly used in:

• Neuronal activity monitoring

Real-time recording of the activity of multiple neurons in the brain, including changes in calcium ion concentration, providing data on the functional connectivity of neurons' neural circuits.

• Assessment of the effects of drug interventions

Our technology can assess the effects of drugs on neural network function. By observing changes in neuronal activity, it helps researchers assess the modulatory effects of different drugs on neural networks.

Spinal cord neural tissue functional imaging services

CD BioSciences utilizes 3D transparency technology and light sheet microscopy imaging to provide our clients with spinal cord neural tissue functional imaging analysis services to help researchers gain insight into the ability and mechanisms of axonal regeneration after spinal cord injury. Through our services, clients can obtain the following information, including but not limited to:

• Identify, track and evaluate the ability of axonal regeneration as well as trajectories.
• Quantify glial activity responses after spinal cord injury and provide detailed reports of quantitative information.

CD BioSciences has a professional team and advanced imaging equipment. The whole process of imaging of nervous tissue functions is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!