Nanoparticles are becoming multifunctional tools in biomedical applications, especially in the field of biomedical imaging. Nanoparticles can be used to diagnose, monitor physical and pathological processes, treat and control biological systems. Nanoparticles are usually less than 100nm in size, and they can be made of materials with different chemical properties, the most common being metals, metal oxides, silicates, polymers, carbon, lipids, and biomolecules. Nanomaterials have diverse chemical surface properties, unique magnetic properties, and adjustable absorption and emission properties. They can be designed in different sizes, shapes, chemical surface properties and hollow, porous or solid structures.

Figure 1: Representative examples of nanoparticles (NP) frequently used for diagnostic and theranostic purposes (Fabian kiessling, et al., 2014).

Nanomaterials have become one of the most powerful imaging tools in molecular imaging due to their diversity and uniqueness. CD BioSciences can synthesize different types of nanoparticles and use nanotechnology for molecular imaging, allowing us to visualize the cell functions and biological processes of living bodies in a non-invasive manner, so as to accurately diagnose diseases at an early stage.

Nanoparticles

Properties of Nanoparticles

Size: 1-100 nm
Shape: spheres, cylinders, platelets, tubes, etc.
Nanoparticles can exist as suspensions, colloids, or dispersed aerosols
High surface area to volume ratio
High mobility in a free state
They may exhibit quantum effects

Application of Nanoparticle Imaging Technology

In vivo imaging of targeted drug delivery
Detect diseases like cancer, cardiac diseases, inflammation, stroke, etc. in their early stages
Tissue imaging and analysis
Cell imaging analysis
Digital pathology & imaging analysis

1. Kiessling F, Mertens M E, Grimm J, et al. Nanoparticles for imaging: top or flop?[J]. Radiology, 2014, 273(1): 10-28.

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