Morphological imaging of nervous tissue is of significant importance in neuroscience research. In neuroscience research, a combination of high-resolution, deep imaging and large tissue section visualization is often required. Typically, through 3D imaging techniques, microscopic imaging combined with staining techniques, researchers can visualize neurons, synaptic connections, and the organization of brain regions. These imaging methods provide researchers with high-resolution images that reveal microscopic details in the nervous system, helping to understand neural circuits and the mechanisms of disease.

Services Overview

CD BioSciences will provide clients with comprehensive morphological imaging analysis of nervous tissue. We specialize in studying the morphology and structure of neuronal cells using a variety of staining techniques, and utilize high-resolution scanning systems that allow for detailed characterization and analysis of neurons, dendritic spines, and axons. We also provide 3D imaging analysis services, including assessment of axonal regeneration after spinal cord injury and morphological imaging of neurons in the mouse brain. In addition, we can perform complete single-cell morphology imaging analysis to help researchers study cell differentiation and metabolic abnormalities in nervous tissues. Through our advanced imaging techniques and analysis methods, gain insight into the complex structure and function of Nervous tissues.

Nervous Tissue Morphology Imaging Services

Nervous tissue morphology imaging analysis services

Nerve cell morphology studies

CD BioSciences helps clients study the morphology and structure of neuronal cells using techniques such as hematoxylin and eosin (HE) staining, Nissl staining, immunohistochemistry (IHC) and cytochemical staining. In addition, we can also help our clients perform qualitative or semi-quantitative analysis of protein expression in nerve cells.

Neuroimaging

A high-resolution scanning system is used to capture images of Golgi-stained nervous tissues or cells for clients, and then uses advanced analysis software to perform detailed characterization and morphological analysis of the following structures, including:

• Neurons
• Dendritic spines
• Axons

Nervous tissue 3D imaging analysis services

CD BioSciences provides comprehensive nervous tissue morphology imaging analysis services utilizing tissue transparency technology and microscopy imaging, our services include but are not limited to:

Neuronal axonal regeneration assessment service

We utilize the tissue transparency technology and light-sheet microscopy 3D imaging to identify, track, and assess morphological information on axonal regeneration after spinal cord injury. Our services help researchers to

• Determine axonal regeneration capacity, trajectory of regenerating axons, and explain axonal regeneration mechanisms.
• Quantify glial activity responses after spinal cord injury.

Mouse brain neuronal morphology imaging service

• Through our tissue transparency technology and precision imaging technology, we can obtain transparent and intact mouse brains for our clients and enable imaging of neurons in the mouse brain.
• We can image neural circuits, subcellular structures, protein complexes, nucleic acids, and neurotransmitters to show our clients the complex fine connectivity and molecular structure in the brain.
• Using chemical methods to label each cell in the brain, we can achieve 3D reconstruction of neurons and map the mouse brain, which helps researchers better understand the spatial distribution and connectivity of neurons.

Nervous tissue intact single-cell morphology imaging analysis services

CD BioSciences can help clients study the intact single-cell morphology of nervous tissue and the effects of differentiation, revealing the cellular differentiation process of nervous tissue and the metabolic abnormalities associated with neurological disorders. Our services mainly include:

Immunofluorescence image acquisition of panoramic brain tissue sections

Using a high-resolution panoramic fast scanning system for immunofluorescence image acquisition of brain tissue sections and with the help of Z-axis panoramic deep imaging, we can perform in-depth analyses of molecular probes, protein labeling, and spatial microenvironmental distribution of tissue morphology.

Single-cell transcriptome level visualization and analysis service

We can fluorescently label more than 10 RNA fragments and acquire quantitative single-cell transcriptome-level analysis and cellular morphology data through confocal-level image acquisition.

CD BioSciences has a professional team and advanced imaging equipment. The whole process of nervous tissue morphology  imaging analysis services is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!