In today's society, viral infection has become one of the main reasons for threatening human health. New lethal viruses are constantly being discovered around the world, including severe acute respiratory syndrome coronavirus 2, Ebola virus and avian influenza virus. Therefore, imaging the detailed process of viral infection and pathological changes is important for the development of antiviral therapies.

Viral Infection Imaging Analysis

Currently, the mechanism of virus infection is mainly understood by analyzing the biochemical changes during virus-cell interaction. However, a series of important physical processes are also involved in the viral infection process, and the physical processes during viral infection are not fully understood. Therefore, studying the mechanical changes of cells during viral infection will help to understand the process of viral infection. Atomic force microscopy is a powerful tool for analyzing viral infection processes.

CD BioSciences has been committed to the development of fluorescent dyes and imaging technology for many years. We can use atomic force microscopy to observe the morphological changes of cells during virus infection. Studying living cell surface morphology will help to better understand the behavior of cells following viral infection, as cell surface morphology is an important indicator of cellular physiological and pathological activity.

Viral Infection Imaging Analysis Workflow

The following are the specific steps of viral infection imaging analysis

Delivery

Image of cells after virus infection
Changes on the cell surface after viral infection
Changes of microtubule proteins in the cytoskeleton
Statistical histogram of changes in Young's modulus of cells during virus infection
Other data that you need

Our Advantages

• Does not require any special handling of the sample
• Visualization of changes in cell surface ultrastructure and cell mechanics of living cells during viral infection
• Experienced scientists provide experimental consultation
• Reasonable price and short turnaround time

CD BioSciences has a professional team and advanced imaging equipment. The entire process of viral infection imaging analysis is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us.  

1. Liu B, Dang D, Yang Y, et al. Nanoscale imaging and mechanical analysis of viral infection on cells by atomic force microscopy[J]. Acta Biochimica et Biophysica Sinica, 2020(11):11.
2. Matula P, Kumar A, et al. Single‐cell‐based image analysis of high‐throughput cell array screens for quantification of viral infection[J]. Cytometry Part A, 2010, 75a(4):309-318.

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Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!