Cellular metabolism is the general term for a series of orderly chemical reactions that occur in cells to maintain life. Metabolism is usually divided into two categories: catabolism can break down large molecules to obtain energy (such as cell respiration); anabolism can use energy to synthesize various components in cells, such as glycogen, protein and nucleic acid. Disorders of metabolic pathways can lead to many common human diseases, such as cancer, diabetes, and neurodegeneration. Therefore, imaging analysis of cell metabolism will help to explore the laws of life activities and provide a powerful basis for the diagnosis and treatment of diseases.

Figure 1. Imaging of the metabolic state of the cells in response to intracellular pO₂ (Penjweini, et al. 2020).

Cell Metabolism Imaging Analysis

As the smallest living unit of life, the average cell diameter is only between 5 and 200 microns. For a long time, the detection of cell metabolism has mainly relied on enzymology, chromatography, mass spectrometry, etc. These methods not only destroy the integrity of cells or organisms, but also it is difficult to perform real-time high-resolution and high-throughput analysis of the metabolic processes of living cells. It is difficult to dynamically and quantitatively regulate cell metabolism, which severely restricts the development of related fields.

CD BioSciences has been committed to the research of new methods in biochemistry and cell biology for many years. We can use a series of high-performance redox metabolism fluorescent probes to achieve high spatiotemporal resolution detection of the redox state of cell metabolism at the level of single cells and living animals. And imaging.

Our Services

Our Advantages

• High-sensitivity optical system to capture high-quality pictures
• Realize the imaging and detection of different cells and different positions
• Real-time dynamic and specific imaging analysis
• High resolution and high throughput analysis
• Experienced scientists provide experimental consultation

CD BioSciences has a professional team and advanced imaging equipment. The entire process of cell metabolism imaging analysis is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us. We will provide you with personalized cell metabolism imaging analysis services according to your needs.

1. Penjweini, Rozhin, et al. "Single cell-based fluorescence lifetime imaging of intracellular oxygenation and metabolism." Redox biology 34 (2020): 101549.

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Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!